Peptide Guide
Plain-English, evidence-graded summaries of 63 research peptides — each with dosing notes, community sentiment, and links to the primary literature.
Follistatin 344 is a glycoprotein that blocks myostatin and activins from the TGF-β family. By switching off myostatin, the natura…
Modified GRF 1-29 is a stabilized synthetic GHRH fragment that triggers the pituitary to secrete the body's own growth hormone. It…
FOXO4-DRI is a synthetic senolytic peptide that selectively kills off senescent 'zombie' cells by separating FOXO4 from p53. The r…
TB-500 is a synthetic version of the body's own thymosin beta-4, a tissue-repair peptide. It helps wounds heal faster and reduces …
ARA-290 (cibinetide) is an EPO-derived peptide that selectively activates the innate repair receptor. It promotes tissue repair an…
BPC-157 is a synthetic peptide derived from a protein in human stomach fluid, known for impressive healing across different tissue…
SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that binds cardiolipin to reduce oxidative stress and support mitocho…
Epitalon is a synthetic tetrapeptide that may activate telomerase to lengthen telomeres and extend cell lifespan. Created by Vladi…
Cagrilintide mimics the pancreatic hormone amylin to promote satiety and slow gastric emptying, and is studied primarily for weigh…
Melanotan 1 is a synthetic alpha-MSH analog that stimulates melanin to darken skin without sun, is FDA-approved for certain condit…
Melanotan 2 is a synthetic peptide acting on melanocortin receptors to drive tanning, increase libido, and possibly curb appetite,…
Semax is an ACTH-derived Russian peptide with potent nootropic and neuroprotective effects that boosts BDNF and cognition, and is …
DSIP is a neuropeptide that promotes delta-wave sleep and regulates sleep structure, potentially normalizing sleep, cutting stress…
Selank is a tuftsin-derived Russian peptide that modulates GABA and serotonin to reduce anxiety and aid cognition without sedation…
A porcine-brain-derived combination of low-molecular-weight neuropeptides and amino acids with BDNF- and NGF-like neurotrophic act…
A synthetic Ala-Asp-Glu tripeptide marketed to stimulate cartilage and connective-tissue regeneration by normalizing chondrocyte p…
A GHRH analog that drives natural pituitary GH production; FDA-approved for pediatric GH deficiency and used off-label for anti-ag…
A naturally occurring copper-bound tripeptide that aids wound healing, collagen synthesis, and skin rejuvenation, used topically f…
A reproductive neuropeptide that stimulates GnRH and downstream LH and FSH release, studied for fertility, hypogonadism, and hormo…
The most selective GHRP, delivering a clean GH release with little effect on cortisol, prolactin, or hunger and minimal side effec…
An angiotensin IV-derived nootropic peptide reported to be 10 million times more potent than BDNF at promoting synaptogenesis, stu…
A community-favorite blend of BPC-157 and TB-500 promoted for accelerated healing and soft-tissue repair, though no study has ever…
An LH-mimicking glycoprotein hormone that supports progesterone in pregnancy and is also used to keep the testes functioning durin…
A gut incretin hormone that raises insulin in a glucose-dependent way, lowers glucagon, increases fullness, and slows digestion, f…
A thymus-extracted peptide complex studied largely in Russia and Eastern Europe as an immune regulator and potential anti-aging ag…
A human cathelicidin antimicrobial peptide that fights bacteria, viruses, and fungi while also modulating inflammation and aiding …
A synthetic GHRH analog that prompts sustained growth hormone release, used for anti-aging, muscle growth, fat loss, and recovery.
An FDA-approved, brain-acting peptide (bremelanotide/Vyleesi) that raises sexual desire via melanocortin receptors, with the stron…
Pinealon is a synthetic Glu-Asp-Arg tripeptide derived from brain-tissue extracts and investigated for neuroprotective and geropro…
AHK-Cu is a copper-bound tripeptide that acts as a growth factor, spurring fibroblast proliferation and VEGF output, with most stu…
GHRP-6 stimulates GH release and strongly increases appetite through ghrelin-receptor activation, producing the largest hunger boo…
Collagen peptides are highly absorbable hydrolyzed collagen fragments (2000-3500 daltons) that, once ingested, stimulate fibroblas…
Adiponectin is a fat-tissue hormone that regulates glucose, fat breakdown, and insulin sensitivity via AMPK activation, with anti-…
Adipotide is a peptidomimetic that targets and kills the blood vessels supplying white fat, causing fat cells to die and be resorb…
Hexarelin is one of the most potent GHRPs, driving strong GH pulses via ghrelin-receptor activation, and it also offers cardioprot…
AOD-9604 is a synthetic peptide based on amino acids 176-191 of growth hormone's C-terminal region with an added N-terminal tyrosi…
Argireline (acetyl hexapeptide-8) is a SNAP-25-derived synthetic peptide marketed as a topical alternative to botox, working by da…
Vilon is a synthetic Lys-Glu dipeptide bioregulator investigated as an immunomodulator and anti-aging agent, said to activate gene…
GHRP-2 is a synthetic hexapeptide that drives reliable growth hormone release through the ghrelin receptor, and is popular for ant…
CJC-1295 with DAC is a GHRH analog whose DAC modification extends its half-life to about 8 days, allowing less frequent dosing whi…
Cortagen (Ala-Glu-Asp-Pro) is a brain-cortex-derived synthetic tetrapeptide bioregulator used to support neuroregeneration, cerebr…
Ibutamoren (MK-677) is an orally active growth hormone secretagogue that mimics ghrelin to raise GH and IGF-1 through pulsatile re…
A seven-amino-acid spadin-derived peptide that selectively blocks the TREK-1 (KCNK2) potassium channel, showing antidepressant-lik…
A 28-amino-acid stomach hormone and the endogenous GHSR ligand, ghrelin triggers growth hormone secretion, increases appetite, and…
A purified FSH-plus-LH hormone preparation that stimulates the gonads to support testosterone production, sperm maturation, and fo…
A 24-amino-acid mitochondrial-derived peptide that protects cells by blocking apoptosis via Bax and Bcl-2 and by lowering oxidativ…
A shellfish-derived biopolymer that binds fats, phosphorus, and bile acids in the digestive tract to limit their absorption, marke…
A TGF-beta superfamily protein and activin type II receptor ligand that negatively regulates erythropoiesis; once hyped as a rejuv…
A Russian-developed Khavinson-family bioregulator peptide targeting bronchial and lung tissue, used to support respiratory functio…
ACE-031 is a soluble ActRIIB fusion protein that neutralizes myostatin and related muscle-growth inhibitors to drive skeletal musc…
Gonadorelin is a pharmaceutical-grade synthetic decapeptide analogue of natural GnRH that stimulates the anterior pituitary to rel…
Prostatilen is a bovine-prostate-derived polypeptide bioregulator used chiefly in Eastern Europe since the 1990s. It is applied to…
AHK (Tripeptide-3) is a synthetic three-amino-acid peptide (Ala-His-Lys) studied for wound healing and anti-aging. It is believed …
Chonluten is a synthetic three-amino-acid peptide bioregulator (L-glutamic acid, L-aspartic acid, L-glycine) intended to support t…
Decapeptide-12 is a synthetic oligopeptide that inhibits tyrosinase to reduce skin hyperpigmentation. It blocks excess melanin pro…
A4 Amyloid Beta (Aβ) is an APP-derived peptide fragment that accumulates as brain plaques in Alzheimer's disease. Its buildup is a…
B7-33 is a synthetic single-chain RXFP1 agonist derived from the B-chain of human gene-2 relaxin, designed to mimic relaxin's vaso…
Cardiogen is a bioregulatory tetrapeptide (Ala-Glu-Asp-Arg) aimed at cardiovascular support, said to stimulate fibroblast prolifer…
Demoxytocin is a longer-lasting synthetic oxytocin analog (made by removing the N-terminal amino group) that activates the oxytoci…
Human Relaxin-2 (recombinant serelaxin) is a peptide hormone acting through RXFP1 to drive systemic and renal vasodilation via nit…
Pramlintide is a synthetic amylin analog that slows gastric emptying, suppresses post-meal glucagon, and boosts satiety; it is FDA…
Retinalamin is a polypeptide bioregulator extracted from cattle retina tissue, used in ophthalmology as a neuroprotective and reti…
Vasoactive Intestinal Peptide (VIP) is a naturally occurring neuropeptide abundant in the brain, gut, and peripheral nervous syste…